Table 1: Literature search detailsDatabases Searched keywords and MeSH titles Number of results Number of relevant articlesPubMed NCBI Osteopathy, arthritis, knee 8801 50PubMed NCBI CAM , knee, osteopathy 342 35PubMed NCBI Acupuncture, osteoarthritis , knee 310 12PubMed NCBI Randomized controlled trial, knee, osteoarthritis, acupuncture 141 10As a weight-bearing joint, the knee can develop osteoarthritis over time due to "wear and tear" . This occurs when the cartilage in the knee joint breaks down and the bone underneath begins to deteriorate, causing pain, stiffness, swelling, and compromised function of the joint. Osteoarthritis is the most common type of knee arthritis and primarily affects middle-aged and elderly people (Srikulmontree 2012). To relieve symptoms, patients can resort to various treatments such as exercise, drug therapy, surgery and alternative methods such as acupuncture. Acupuncture is a complementary or alternative medicine originating in ancient China. It involves inserting needles into specific pressure points on the human body. It is believed to be a treatment for various conditions, especially those associated with severe pain, such as knee osteoarthritis (OA). However, although acupuncture has been used for thousands of years (White and Ernest 2004), the effectiveness of this treatment method has not been conclusively established. This critical literature review will compare two published articles that study its effects on patients with knee osteoarthritis. Article 1Tukmachi et al (2004) investigated the effectiveness of acupuncture alone and as adjunctive treatment for knee osteoarthritis using an open-label randomized controlled trial. . Adult patients with a history of more than six...... middle of article ......ntree, T. 2012, "Osteoarthritis", American College of Rheumatology, .Stinner, DJ & Tennent, DJ 2012 , “Loss to follow-up poses a risk to study validity,” American Academy of Orthopedic Surgeons, , no. February 2012. Suarez-Almzazor, ME, Looney, C., Liu, Y., Cox, V., Pietz, K., Marcus, DM & Street Jr., RL September 2010, "A randomized controlled trial of acupuncture for osteoarthritis of the knee: effects of patient-provider communication", Arthritis Care Res, vol. 62, no. 9, pp. 1229-1236.Tukmachi, E., Jubb, R., Dempsey, E. & Jones, P. 2004, "The effect of acupuncture on symptoms of osteoarthritis of the knee - an open-label randomized controlled study", Acupuncture in Medicine: Journal of the British Medical Acupuncture Society, vol. 22, no. 1, pp. 14-22.White, A. & Ernest, E. 2004, 'A brief history of acupuncture', Rheumatology, vol. 43, no. 5, pp... 662-663.