reflected in urinary values).3Conrad Howe, Balraj Kang, Julie Kim, Brittany Kraft, Kevin Kurtzner, Michael Kutsyk“Is BPA a concern for dentistry? » Bisphenol A (BPA) is a synthetic compound used throughout the world. in the manufacture of plastics and epoxy resins. BPA derivatives are present in resin-based sealants and composites used in dentistry.1 Some of these compounds include bis-DMA (BPA dimethacrylate), bis-GMA (BPA glycidyl methacrylate), and BADGE ( diglycidyl ether of BPA).1 Although pure BPA is not used in dental resins, bis-DMA has been shown to have the ability to be hydrolyzed to BPA by salivary esterases.1 This is a potential source of concern due to the numerous adverse health effects associated with BPA. These effects are likely due to BPA's ability to bind to nuclear estrogen receptors and interfere with endocrine signaling.1 It is therefore of interest to determine the estrogenic potential of dental resins over time. A study carried out at the Institute of Biomaterials and Bioengineering in Tokyo analyzed the release of BPA from orthodontic brackets submerged in water. ...