IntroductionCrohn's disease is a chronic inflammatory disease of the gastrointestinal tract that belongs to a group of diseases known as inflammatory bowel diseases (IBD). Crohn's disease is defined as transmural inflammation with skip lesions that can affect the gastrointestinal tract from the mouth to the anus (Mulder, Noble, Justinich, & Duffin, 2013). In Crohn's disease, the immune system attacks the gastrointestinal system and can cause chronic inflammation of the digestive tract. Crohn's disease has a variety of symptoms, including abdominal discomfort, diarrhea, rectal bleeding, fever, and weight loss. Crohn's disease can also affect the joints, skin, eyes and cause kidney stones, gallstones, and other conditions (Warner & Barto, 2007).Physiology of Crohn's diseaseCrohn's disease can affect no any part of the gastrointestinal tract, from the mouth to the anus, but it most commonly affects the end of the small intestine (the ileum) and the beginning of the colon. It can simultaneously involve different areas of the gastrointestinal tract with an alternation of diseased segments and normal segments. Crohn's disease affects the entire thickness of the intestinal wall and can be complicated by fistulas and abscesses. Crohn's disease can also contain granuloma cells, called granulomatous enteritis or granulomatous colitis (Warner and Barto, 2007). The cause of Crohn's disease is unknown, but researchers believe it is the result of an abnormal reaction of the body's immune system. Normally, the immune system protects people from infections by identifying and destroying bacteria, viruses, or other potentially harmful foreign substances. Researchers believe that in Crohn's disease, the immune system attacks bacteria, food, and other substances... middle of article......aging Crohn's disease. It is particularly useful for evaluating a fistula around the anal region (pelvic MRI) or small intestine (MR enterography) (NDDIC, nd). If the patient has signs and symptoms suggestive of Crohn's disease but other diagnostic tests are negative, their doctor may perform a capsule endoscopy. The camera takes pictures and checks for signs of Crohn's disease. An endoscopy with biopsy is often still necessary to confirm the diagnosis of Crohn's disease and exclude other causes of their symptoms (NDDIC, n.d.). A barium enema is often performed to evaluate their large intestine with an x-ray. The barium dye coats the lining of the intestine, creating a silhouette of their rectum, colon, and part of their small intestine visible on an X-ray. This test is rarely performed due to the availability of colonoscopy and CT scanning (NDDIC, n.d.)..).