In recent decades, nanotechnology has been considered as an applied technology. This technology produces and controls materials, tools and new molecular-atomic sized systems created from the combination of physical, chemical and biological sciences. New Nano-sized materials have new benefits and features that didn't exist before. Nanotechnology has different types of operations, such as: food, drugs, medical diagnosis, biotechnology, electronics and computing, communication, transportation, energy, security, health and environment, aerodynamic spacing, etc. unique characteristics of each nano martial type size, shape, biocompatibility and solubility are important factors in biological effectiveness.HistoryA) Medical development and appearance of nanomedicineNano Medical is an application of approaches, theories, devices and nanoscale structures to identify, prevent or treat diseases through the detection and repair of damaged tissues. at the biomolecular level. The main focus of nanomedicine is pathology and treatment facilities at the molecular and tiny scale. According to Majo et al.'s research, major nanomedicine application areas that present computational challenges include: drug delivery, implantable devices, diagnostics, prevention, and therapeutics. Nanoparticles can be used as vectors for drugs or certain organic molecules. Nanoscale delivery involves transferring nanoscale objects into the body and penetrating them into cells. The high cost of drug development, in the range of $3,000 to $11.5 million, is one of the obstacles to progress in this area. Many nanoscale implantable devices, such as nanorobots, can be designed to monitor diseases. For example, nanoscale devices can be attached to the patient and...... middle of paper ......d quantify tumors in the near-infrared region. 2009, Elsevier. p. 216-224.22. Lanza, GM, et al., Targeted delivery of antiproliferative drugs to vascular smooth muscle cells with implications of magnetic resonance imaging nanoparticle contrast agent for the rational treatment of restenosis. 2002, Am Heart Assoc. p. 2842-2847.23. Popovtzer, R., et al., Targeted gold nanoparticles enable molecular imaging of cancer using computed tomography. 2008, ACS Publications. p. 4593-4596.24. Chaimovich, A. and MS Shell, Coarse-graining errors and numerical optimization using a relative entropy framework. p. 094112.25. Xia, XR, NA Monteiro-Riviere and JE Riviere, An index for the characterization of nanomaterials in biological systems, Nature Publishing Group. p. 671-675.26. Shaw, SY et al., Disruptive profiling of biological activity of nanomaterials. 2008, National Academic Sciences. p. 7387.