The introduction of any innovation or invention in medical technology requires sufficient testing to determine its safety and effectiveness. The fact that clinical studies are carried out on people generates an important ethical debate concerning respect for these patients. Interestingly, this ethical debate gained significant attention after World War II, during the Nuremberg war crimes trials, during which the judgments of those who conducted biomedical experiments on prisoners were determined ( The Belmont Report, 3). The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research was established to establish ethical guidelines for research involving human subjects (2). The Commission achieved this through the publication of the Belmont Report, which summarizes the Commission's conclusions resulting from its four days of deliberations (2). Examination of the Belmont Report reveals that the ethical principles of respect for persons, beneficence, and justice have broad application in biomedical research using human patients. Respect for the people participating in the study is supported by the application of ethical principles on autonomy. . First, “individuals should be treated as autonomous agents” (Belmont Report, 4). An autonomous individual is someone who can make a decision through their own reasoning. People have different degrees of autonomy for different reasons, such as age or disability. This leads to the second principle according to which “people losing their autonomy have the right to protection” (4). Those who are too young to fully understand a decision, as well as those who have been incapacitated in some way, need some protection. In the absence of pr...... middle of paper ......t, doctors must do everything possible to demonstrate respect for people, beneficence and justice. Respect for persons means allowing individuals to make their own decisions, unless they are incapable of doing so, which is done through informed consent. Respecting beneficence consists of caring for the well-being of others; In the medical industry, the best way to do this is to weigh the risks and benefits and try to get the most favorable ratio between the two. Respect for justice ensures that the benefits and burdens of a study are distributed equally, so that no individual must bear all the burdens or receive all the benefits. The Belmont Report provides "basic ethical principles and guidelines" that physicians conducting medical research studies can follow to provide the most ethical treatment possible to their patients (The Belmont Report 2).