What is the 8th leading cause of death in the United States? (Please don't guess, you'll find it at the end of this article!) First, some horrifying points: 44,000 Americans die every year from medical errors, more people die from this reasons such as road accidents, breast cancer or AIDS. The total national cost calculated as follows: loss of income, loss of production, health care cost is estimated between $17 billion and $29 billion and this is a modest estimate that does not include related preventable adverse events medication and repeated diagnostic tests. But not all the cost. can be directly measured: loss of trust in the medical system, decreased patient and healthcare provider satisfaction, shortage of high-quality healthcare providers due to reduced college enrollment and lower level of population in good health. Yet, silence surrounds this issue, nothing is exposed to the public eye, anecdotal cases do not reveal the pain of a family or a child. In this report: “To err is human”, safety is defined as the absence of accidental injuries in the first place. time defines the safety goal from the patient's perspective. Error is defined as the failure of a planned action to be carried out as intended or the use of a wrong plan to achieve an objective. Errors can occur at all stages of care, from diagnosis to treatment and preventive care. Since this is a planned intervention in the medical system, the emphasis must shift from blaming individuals for past errors and focus on preventing future errors by implementing safety into the system. IOM Committee on Health Care Quality in America, 1998 produced a report that addresses issues related to patient health. concerns related to care and overall quality, the major force for this change is intrinsic, coming from health care providers with...... middle of paper ...... I must negotiate six major challenges Rethinking the care processes in order to serve more effectively, using tools and providing care that lag far behind biomedical knowledge. Use information technologies that are ready and user-friendly for the patient and the healthcare team. Managing growing knowledge. Coordination of care according to the patient's condition and services. Improve teamwork. The final challenge is daily life: integrating the care process and outcome measures into their daily work. The system transitioning to the 21st century must be ready and prepare the workforce. At least three approaches can be taken to support the transition:1. Rethink how healthcare is trained, including evidence-based learning/practice, using a multidisciplinary approach.2, Change how health professions are regulated3. Examine how the accountability system may restrictively support changes in care delivery.