Place the introduction here, to include the thesis statement. Insulin resistance plays an important role in the fertility of women with polycystic ovary syndrome. Myo-Inositol improves fertility and alleviates many of these symptoms. Polycystic ovary syndrome is a condition that affects many different parts of the body, not just the ovaries. The list of conditions associated with polycystic ovarian syndrome is long, ranging from skin tags, dark skin spots and hirsutism (male hair growth) to liver disease, obesity and insulin resistance. Symptoms that contribute to infertility are irregular menstrual cycles, androgen excess, and chronic anovulation (Genazzani, Lanzoni, and Riccieri 139). Polycystic ovary syndrome is abbreviated to its acronym PCOS by the medical community and women who have been diagnosed with polycystic ovary syndrome. he. Polycystic ovary syndrome is an endocrine disorder that affects at least 10% of women living in the United States. This disorder is predominant in reproductive females aged 12 to 45 years (Ban 635). Many women are only diagnosed with polycystic ovarian syndrome when conception is desired. To be diagnosed with polycystic ovarian syndrome, women must meet two of the three required criteria. Women will be tested for endocrine abnormalities in laboratory tests, radiological abnormalities in ultrasound examinations, and clinical features, such as amenorrhea or central obesity. Additional etiologies must also be considered, or even excluded, before the diagnosis of polycystic ovary syndrome can be made. Some of these exclusions are adrenal or ovarian tumors, congenital adrenal hyperplasia, and Cushing's syndrome (ban 638). An example of endocrine testing abnormalities would be an exc...... middle of article ......-1454 . Premier Academic Research. Internet. March 28, 2014. Raffone, Emanuela, Pietro Rizzo and Vincenzo Benedetto. “Insulin sensitizing agents alone and as co-treatment with R-FSH for ovulation induction in women with PCOS.” Gynecological Endocrinology 26.4 (2010): 275-280. Premier Academic Research. Internet. April 5, 2014. Sedwick, Caitlin. “Breaking insulin resistance.” Plos Biology 11.2 (2013): 1. Academic Research Premier. Internet. April 2, 2014.Unfer, V., et al. “Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials.” Gynecological Endocrinology 28.7 (2012): 509-515. Premier Academic Research. Internet. April 7, 2014.Zacche, Martino M. et al. “Effectiveness of myo-inositol in the treatment of skin disorders in young women with polycystic ovarian syndrome.” Gynecologic Endocrinology 25.8 (2009): 508-513. Premier Academic Research. Internet. March 22 2014.