DiscussionChlorpyrifos in cattleMean chlorpyrifos residue levels in cattle meat samples collected in the northeast were not significantly different from those collected in the southwest. city ​​of Faisalabad, 0.297 ± 0.006 ppm, and 0.373 ± 0.001 ppm, during the months of July 2009 to December 2009 (Table 1). These values ​​in the present study are higher than their corresponding values ​​in the literature. No differences in chlorpyrifos concentrations were observed in the muscles, kidneys, liver and lungs of cattle in summer and winter, while Pagliuca et al. (2006) reported a gradual decrease in positive samples from fall to spring and their results were confirmed by Gazzotti et al. (2008). Chlorpyrifos was found in almost 15% of the samples analyzed and its detected value was several times higher than the MRL value established by the USFDA. In some studies conducted on milk, the main pesticidal pollutant was chlorpyrifos (Gazzotti et al., 2008) and its contamination ranged from 5 to 18 mg/kg. In bioaccumulation experiments, fish meat was detected to accumulate chlorpyrifos up to 5.9 ng/g (Varo et al., 2002).Lembda-cyhalothrin in cattleResidue values ​​of Lembda-cyhalothrin in the meat of cattle from the northeast are higher than those of the meat from the southwest of Faisalabad city, 4,790 ppm and 4,521 ppm, respectively (Table 1). The concentration of lembda-cyhalothrin remained the same during summer and winter seasons in bovine muscle, kidney, liver and lung samples. Lembda-cyhalothrin was proportionally more common in meat than other pesticides and was detected in almost 25% of samples. This high frequency could be explained by its wide use as an insecticide and ectoparasite on livestock (Gazzotti et al., 2008). unlike ...... middle of paper ......endosulfan than those collected from three sites northeast of Faisalabad city.• Residues of chlorpyrifos, cypermethrin, lambda-cyhalothrin and endosulfan in the meat of cattle remained the same in summer and winter. Recommendations: The concentration of all pesticide residues found in the present study is alarming. The higher concentration of pesticide residues poses a potential threat to both livestock and humans. Our data deserves special attention. All products exceeding authorized limits may be declared unsanitary due to the toxicological risks associated with them. The public and private sectors must cooperate to solve the problem jointly. Acknowledgments: Financial support from Higher Education Commission Islamabad and Government of Pakistan under research project number 20-726 is highly appreciated..