The accepted meaning of toxicology is known as “the art of toxic substances”. A more graphic definition of toxicology is "the study of the harmful impacts of chemicals, natural or physical executors on living life forms." These adverse impacts can occur in many forms, ranging from rapid or more painful death to changes that are not understood until months or even years later after the effect. Learning about how venomous executors (agents) harm our bodies has progressed alongside therapeutic knowledge/information. Chronic advances in toxicology began quickly with the first cavemen! They distinguished harmful plants and creatures and used their concentrates to hunt or in their hunting combats. Learning about how venomous enforcers harm the figure has progressed alongside therapeutic information. Historical advances in toxicology began with cave dwellers distinguishing between harmful plants and creatures and using their concentrates for hunting or warfare. Over time, mischief became widely used. The main people who are harmed include Socrates, Cleopatra, and Claudius. During the renaissance and edification, some of the main ideas of toxicology began to come to fruition. The right measure separates a toxic substance from a cure. state executions. Over time, mischief became widely used. Exceptional victim harms include Socrates, Cleopatra and Claudius during the Renaissance and Enlightenment era, some fundamental ideas of the addictol...... middle of paper. ....f Hippocrates. He played a vital role in the advancement of toxicology by attempting to control the absorption of toxic materials in therapy and overdose. Around 400 BC, he introduced insightful medicines (rational medicine) and included various toxins, and more. drafted guidelines that could be recognized as primitive standards of toxicology. Around the middle of the 19th century, this was considered a chemical uprising. Many natural chemicals were released into the environment, this disaster prepared and released new substances like none existed in the characteristic world. With the processing and use of these chemicals, and the requirement to protect people from the hazardous effects of mechanical chemicals; toxicology eventually developed to integrate its current extensions: pharmacology, clinical toxicology and natural toxicology.