Aspartame was discovered by James Shatter. He is a chemist at GD Searle, where he accidentally discovered aspartame. Aspartame is a substance 180 times sweeter than sugar, but it contains zero calories. In the spring of 1967, Searle began conducting safety tests for aspartame, necessary for FDA approval. In the fall, a biochemist named Dr. Harold at the University of Wisconsin conducted a test of aspartame on baby monkeys. Without first informing the Searle company. The test results were negative. Out of seven monkeys, one dies and the other six die due to convulsions. On December 18, 1970, the Searle Company presented a food and safety strategy for aspartame. The company believed this would give the FDA a positive view on sugar. In the spring of 1971, a neuroscientist named Dr. John Olney told Searle that aspartic acid had caused holes in the brains of infant mice. Until now, aspartame didn't seem very good for anyone. In February 1973, after spending ten million dollars testing the safety of aspartame, Searle finally sought FDA approval. They presented around a hundred studies claiming that aspartame is safe. On March 5, the FDA's top scientist reviewed aspartame's safety data sheet and said the information was inaccurate. For aspartame to be safe, additional testing had to be done. In May 1974, the Searle company had to go to court to prove the accuracy of its data. Searle's attorney, Jim Turner, meets with company representatives to discuss the drone problem with security data. In July, the FDA gave aspartame its first approval for use in dry foods. August 1974, Jim Turner and John Olney file disagreements over the approval of aspartame. March 24, 1976 Jim and Olney's petition leads to investigation...... middle of article...... Professor Ron Walker, Emeritus Professor of Food Science, School of Biological Sciences, University of Surrey, UK -United. The new epidemiological data revealed no indication of adverse effects on human reproductive parameters from cyclamate used as a food additive or from workplace exposure to cyclohexylamine. European Union Of the four sugars I studied, I chose sucralose. I chose this sugar because it doesn't have many side effects like saccharin, aspartame and sodium cyclamate. It is also used for most of the foods and drinks we consume so my body system can easily interact with it. .elhurst.edu.comwww.sucralose.comwww.cyclamte.org