Many elderly patients take NSAIDs chronically. There are many adverse effects associated with chronic NSAID use, including the risk of acute kidney injury, stroke/myocardial infarction, peptic ulcer disease, and worsening of other chronic conditions. , including heart failure and hypertension. NSAIDs may also interact with a number of medications (warfarin, corticosteroids), thereby increasing hospitalizations among the elderly population. Adverse drug reactions are more likely to affect geriatric patients due to physiological changes that occur with aging, such as changes in kidney function and metabolic changes. Say no to plagiarism. Get a tailor-made essay on “Why violent video games should not be banned”?Get the original essayNonsteroidal anti-inflammatory drugs are a common class of painkillers typically used chronically to treat pain such as musculoskeletal pain. -skeletal, including osteoarthritis. It is commonly used in the elderly population. About 40% of people over the age of 65 fill one or more NSAID prescriptions each year, not including over-the-counter NSAIDs. The main risk factors for admissions for adverse events are older age, polypharmacy, comorbidity and taking potentially inappropriate medications. A study highlighted the need for an adverse event prediction tool to identify high-risk patients (elderly population) and thus target appropriate interventions towards the prevention of adverse events. associated hospital admissions. The study further highlighted the role of primary care physicians and pharmacists in communities in identifying patents at risk of ADR. (7). There are currently no validated tools to assess the risk of adverse events in primary care. According to a systematic review and meta-analysis carried out by means of a computerized search of the main databases, between 1988 and 2015, relating to hospitalizations induced by adverse drug reactions in patients over 60 years of age, NSAIDs were the most common drug-related adverse reactions. effects leading to hospitalizations ranging from 2.3 to 33.3%. According to a prospective cohort study performed, participating pharmacies were called the intervention group (IG) and received feedback on medication dispensing in non-selective NSAID users aged = 60 years at risk for UGI. damage and were responsible for selecting patients to improve the prescription of ns-NSAIDs, in collaboration with primary care physicians. NSAID users from other pharmacies without concomitant use of gastroprotective agents (GPA) were followed in parallel as a control group (CG). Changes in UGI risk of NS-NSAID users between baseline and follow-up measurements, assessed by either the addition of GPA or NS-NSAID discontinuation, were compared between the two arms of the study. The results showed that persistent NSAID users among selected IG patients had a 7% additional probability of reducing the risk of IGU at follow-up (odds ratio 0.93, 95% confidence interval 0, 89-0.97) compared to CG patients. In the IG study, 91% of selected IG patients with a risk of UGI due to NS-NSAIDs at baseline no longer had an increased risk at follow-up due to discontinuation of NS-NSAID treatment or withdrawal. concomitant use of GPA. Keep in mind: this is just a sample. Get it now.