Morphological growth and development occurred by factors affecting the properties of cells. These variations occur by altering the functional characters of cells that cause morphological, developmental, and age-related deviations. As a result, based on scientific research and analysis of scientific experiments, it was summarized that the effects of morphological changes are formed on malignant cells. Much scientific research has been conducted on the morphological development of distributions affecting functional development. In 1996, Sharon Freeman, Lily Cherny, and Haim Sohmer published an article titled "Thyroxine Affects Physiological and Morphological Development of the Ear" discussing theories on the development of otoacoustic distortion product emissions (DPE) which accounted for cochlear amplifier activity in hyperthyroidism. In hearing research, scientists compared the onset and development of auditory nerve and brainstem-evoked responses representing overall cochlear function and morphological development of the ear. (1) For this research, the rats were divided into neonatal hyperthyroid rats (n=10) and control group rats (n=10). These rats were compared based on developmental responses to auditory nerve, brainstem, and bone responses. Otoacoustic emissions (DPE) of distortion products had been recorded at previously high (8 kHz) and low (3 kHz) levels. At the end of the hearing study, it was found that the results of the morphological comparison revealed a consistent difference between the level of development of the outer ear and the middle ear. As a result, rats injected with thyroxine showed obvious signs of neonatal hyperthyroidism of the cochlea, such as otoacoustic emissions of distortion products. (1) Similarly, scientist RP Birth and...... middle of article...... all results suggest that prenatal exposure to Zeranol or DES induces abnormal testicular differentiation in the mouse. (4) The final experiment is to understand neurodegenerative disease. In 1996, Barkats analyzed the number of granule cells in the dentate gyrus, which varied among inbred strains of mice. Scientists were hypothesizing about age-related morphological changes in the dentate gyrus in both animals and humans. Therefore, the aim of this experiment was to study "the constraint difference in hippocampal structure changes in old C57BL/6J (B) and DBA/2J (D) mice compared to younger ones." » (5) At the end of the experiment, Barkats concluded that examination of the hippocampus in mouse strains showed that neuroanatomical parameters were still reduced with age and that the population of granule cells in the dentate gyrus could be influenced by certain hereditary factors..